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周辺地図

2017年9月
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A. 原著論文・総説

Congenit Anom 57巻1号表紙

2017年 ※本研究室が主体として行った英語論文(査読あり)には通し番号が振られています。

31. Morphogenesis of the middle ear during fetal development as observed via magnetic resonance imaging
Ohtsuki S, Ishikawa A, Yamada S, Imai H, Matsuda T, Takakuwa T, Anat Rec 2017, in press(概要)

■ Katsube M, Yamada S, Miyazaki R, Yamaguchi Y, Makishima H, Takakuwa T, Yamamoto A, Fujii Y, Morimoto N, Ito T, Imai H, Suzuki S, Quantitation of nasal development in the early prenatal period using geometric morphometrics and MRI: A new insight into the critical period of Binder phenotype. Prenatal Diag 2017, in press, 10.1002/pd.5106

■ Saito A, Tsujikawa M, Takakuwa T, Yamada S, Shimizu A, Statistical shape model of nested structures based on the level set, MICCAI, 2017, in press.

30. Takakuwa T, 3D analysis of human embryos and fetuses using digitized datasets from the Kyoto Collection, Anat Rec 2017, in press (総説)[2008年から開始したヒト胚子・胎児研究についてまとめました ]

29. Osaka M, Ishikawa A, Yamada S, Uwabe C, Imai H, Matsuda T, Yoneyama A, Takeda T, Takakuwa T, Positional changes of the ocular organs during craniofacial development, Anatomical Record, 2017, in press, DOI: 10.1002/ar.23588(概要)

■ Xiang Ji, Takakuwa T, Takahashi M, Iijima H, Morino S, Ishihara M, Kawagoe M, Hadanaka Y, Umezaki F, Yamashita M, Aoyama T, Postpartum radiographic changes in pelvic morphology and its relation with symptoms of pregnancy-related symphysis pain, Clin Exp Obst Gynecol, 2017, in press

■ Kishimoto M, Saito A, Takakuwa T, Yamada S, Matsuzoe H, Hontani H, Shimizu A, A spatiotemporal statistical model for eyeballs of human embryos, IEICE Transactions  on INF & SYST, E100-D (7), 2017, 1505-1515. 10.1587/transinf.2016EDP7493 [Open Access]

28. Okumura M, Ishikawa A, Toyama T, Yamada S, Uwabe C, Imai H, Matsuda T, Yoneyama A, Takeda T, Takakuwa T, Cartilage Formation in the Pelvic Skeleton during the Embryonic and Early-Fetal Period, PLoS ONE 12(4): e0173852. https://doi.org/10.1371/journal. pone.0173852 [Open Access](概要)

27. Yoshida R, Ishizu K, Yamada S, Uwabe C, Okada T, Togashi K, Takakuwa T, The dynamics of gyrification in the human cerebral cortex during development, Congenit Anom, 57 (1) 8-14, 2017, DOI: 10.1111/cga.12179, 10.1111/cga.12181

査読なし

■ Takakuwa T, Muranaka T, Yamada S, Three-dimensional Analysis of the Bronchial Branching in Human Embryonic Stages- Progress Overview FY2016 -, Proceedings of The 2nd  International Symposium on Multidisciplinary Computational Anatomy, 2017, 45-48.

■ Takakuwa T. A novel strategy to reveal the latent liver abnormalities in human embryonic stages from a large embryo collection,  in press.

■ 高桑徹也、尾脇なつみ;ヒト胚子期、胎児期初期における上気道、口腔の形態形成 (3D morphology and morphometry of the nasal and oropharynx region during the human embryonic and early fetal period), Photon Factory Activity Report 2016 #34(2017) [BL-14C/2015G574]

pd4818-toc-0001

Prenatal Diagnosis, 36(4), 2016 表紙

2016年

■ Sasaki K, Nakamura T, Okamoto I, Yabuta Y, Iwatani C, Tsuchiya H, Seita Y, Nakamura S, Shiraki N, Takakuwa T, Yamamoto T, Saitou M. The Germ Cell Fate of Cynomolgus Monkeys Is Specified in the Nascent Amnion. Develop cell, 2016 ;39 :169-185. DOI: doi: 10.1016/j.devcel.2016.09.007.

26. Ozeki-Satoh M, Ishikawa A, Yamada S, Uwabe C, Takakuwa T. Morphogenesis of the Middle Ear Ossicles and Spatial Relationships with the External and Inner Ears during the Embryonic Period, Anat Rec 299:1325–1337, 2016, DOI 10.1002/ar.23457, (概要)

25. Takakuwa T, Koike T, Muranaka T, Yamada S, Uwabe C. 2016. Formation of the circle of Willis during human embryonic development. Congenit Anom (Kyoto) 2016; 56, 233–236, DOI: 10.1111/cga.12165

■ Mehemed TM, Fushimi Y, Okada T, Kanagaki M, Okada T, Yamamoto A, Takakuwa T, Yamada S, Togashi K, Magnetic resonance imaging of pituitary gland and postsphenoid ossification in fetal specimens, Am J Neuroradiology 37 (8):1523-7, 2016, 10.3174/ajnr.A4808. [Open Access]

24. Hirose A, Nakashima T, Shiraki N, Yamada S, Uwabe C, Kose K, Takakuwa T, 3D models related to the publication: Morphogenesis of the liver during the human embryonic period, MorphoMuseuM 1(4) e1, 2016, doi: 10.18563/m3.1.4.e1

23. Kobayashi A, Ishizu K, Yamada S, Uwabe C, Kose K, Takakuwa T, Morphometric human embryonic brain features according to developmental stage, Prenatal Diagnosis, 36:338–345, 2016, DOI: 10.1002/pd.4818, DOI: 10.1002/pd.4786.

Anatomical Rec. 299(1) 2016表紙

Anatomical Rec. 299(1) 2016表紙

22. Ueno S, Yamada S, Uwabe C, Männer J, Shiraki N, Takakuwa T, The digestive tract and derived primordia differentiate by following a precise timeline in human embryos between Carnegie stages 11 and 13, Anatomical Rec 2016,  299, 439-449, DOI: 10.1002/ar.23314s,  (概要)

21. Ozeki-Sato M, Yamada S, Uwabe C, Ishizu K, Takakuwa T, Correlation of external ear auricle formation with staging of human embryos, Congenit Anom (Kyoto) 56, 86-90, 2016, DOI: 10.1111/cga.12140,  (概要)

20. Nako A, Kaigai N, Shiraki N, Yamada S, Uwabe C, Kose K, Takakuwa T, 3D models related to the publication: Morphogenesis of the stomach during the human embryonic period, MorphoMuseuM, 1(4) e3,2016, doi: 10.18563/ m3.1.4.e3

■ Kishimoto H, Yamada S, Kanahashi T, Yoneyama A, Imai H, Matsuda T, Takeda T, Kawai K, Three-dimensional observation of palatal muscles in the human embryo and fetus: development of levator veli palatini and clinical importance of the lesser palatine nerve, Developmental Dynamics 245: 123–131, 2016,  DOI: 10.1002/dvdy.24382, DOI: 10.1002/dvdy.24364

19. Ueda Y, Yamada S, Uwabe C, Kose K, Takakuwa T, Intestinal rotation and physiological umbilical herniation during the embryonic period, Anatomical Record 299, 197-206, 2016, DOI: 10.1002/ar.23296

18. Kanahashi T, Yamada S, Tanaka M, Hirose A, Uwabe C, Kose K, Yoneyama A, Takeda T, Takakuwa T, A novel strategy to reveal the latent abnormalities in human embryonic stages from a large embryo collection, Anatomical Record, 299,8-24,2016  10.1002/ar.23281(概要)*299(1),2016の表紙に採用されました。DOI: 10.1002/ar.23206 (cover page)

査読なし

■ Takakuwa T, Muranaka T, Yamada S, Three-dimensional Analysis of the Bronchial Branching in Human Embryonic Stages- Progress Overview FY2015 -, Proceedings of The 2nd  International Symposium on Multidisciplinary Computational Anatomy, 2016, 43-46. 

■ 高桑徹也、大坂美穂;ヒト器官形成期の視覚器の位置の移動について (The movement of Visual organs during cranio-facial development), Photon Factory Activity Report 2015 #33(2016)B [BL-14C/2015G574]

2015年
2015_3_cover_image-1

MorphoMuseuM 1(3) 2015 表紙

17. Toyoda S, Shiraki N, Yamada S, Uwabe C, Imai H, Matsuda T, Yoneyama A, Takeda T, Takakuwa T, Morphogenesis of the inner ear at different stages of normal human development.   Anatomical Record, 298:2081–2090 (2015), doi: 10.1002/ar.23268 *AR WOW Video article

16. Toyoda S, Shiraki N, Yamada S, Uwabe C, Imai H, Matsuda T, Yoneyama A, Takeda T, Takakuwa T, 3D models related to the publication: Morphogenesis of the inner ear at different stages of normal human development. MorphoMuseuM 1 (3)-e6. doi: 10.18563/m3.1.3.e6   *1巻3号の表紙に採用されました。

15. Shiraishi N, Katayama A, Nakashima T, Shiraki N, Yamada S, Uwabe C, Kose K, Takakuwa T, 3D model related to the publication: Morphology of the human embryonic brain and ventricles,  MorphoMuseuM 1 (3)-e3. doi: 10.18563/m3.1.3.e3. [OpenAccess]

14. Zhang X, Aoyama T, Takaishi R, Higuchi S, Yamada S, Kuroki H, Takakuwa T, Spatial change of cruciate ligaments in rat embryo knee joint by three-dimensional reconstruction.PLoS One. 2015 Jun 22;10(6):e0131092. doi: 10.1371/journal.pone.0131092. eCollection 2015., [OpenAccess]

13. Shiraishi N, Katayama A, Nakashima T, Yamada S, Uwabe C, Kose K, Takakuwa T, Morphology and morphometry of the human embryonic brain: A three-dimensional analysis, NeuroImage, 2015, 115, 96-103, 10.1016/j.neuroimage.2015.04.044, (概要)[OpenAccess]

12. Shiraishi N, Katayama A, Nakashima T, Yamada S, Uwabe C, Kose K, Takakuwa T, Three-dimensional morphology of the human embryonic brain, Data in Brief, 2015, 4, 116-118, 10.1016/j.dib.2015.05.001 [OpenAccess]

11. Endo A, Ueno S, Yamada S, Uwabe C, Takakuwa T, Morphogenesis of the spleen during the human embryonic period,  Anatomical Rec, 2015, 298, 820-826, doi: 10.1002/ar.23099(概要) [OpenAccess]

10. Taketani K, Yamada S, Uwabe C, Okada T, Togash K, Takakuwa T, Morphological features and length measurements of fetal lateral ventricles at 16–25 weeks of gestation by magnetic resonance imaging, Congenit Anom (Kyoto), 2015, 55, 99-102. doi: 10.1111/cga.12076(概要) [OpenAccess]

査読なし

■ Yamada S, Hill M, Takakuwa T, Chapter 5, Human Embryology, (Wu B, editor) New Discoveries in Embryology Open Access Publisher, Rijeka, Croatia, 2015, pp 97-124. ISBN 978-953-51-2182-4

■ 高桑徹也、豊田彩希、白木直人;ヒト胚子内耳形成の3次元的解析 (3D morphogenesis of inner ear of human embryo), Photon Factory Activity Report 2014  [BL-14C:2013G514]

■ 岸本 将志、斉藤 篤、大坂 美穂、高桑 徹也、山田 重人、清水 昭伸、ヒト胚子の眼球を対象とした時空間統計モデルに関する初期検討、信学技報, 2015

2014年 
ar22774

Anatomical Rec. 297(5) 2014表紙

9. Takaishi R, Aoyama T, Zhang X, Higuchi S, Yamada S, Takakuwa T; Three-dimensional reconstruction of rat knee joint using episcopic fluorescence image capture, Osteoarthritis Cartilage, 2014; 22(10), 1401-1409. 10.1016/j.joca.2014.06.016(概要), [OpenAccess]  

8. Kaigai N, Nako A, Yamada S, Uwabe C, Kose K, Takakuwa T, Morphogenesis and three-dimensional movement of the stomach during the human embryonic period, Anat Rec (Hoboken). 2014 May;297(5):791-797. doi: 10.1002/ar.22833 ,  2014 May;297(5):C1. doi: 10.1002/ar.22774. (概要), [OpenAccess]

 (Editorialで紹介されました)[OpenAccess]

 (297巻5号の表紙に採用, AR WOW video articleに選定されました) [OpenAccess]

査読なし

■ Takakuwa T and Kanahashi T, Two cases of liver agenesis detected in externally normal human embryos: A novel abnormality resulting in abortion during the embryonic period ( 外表正常ヒト胚子にみられた肝臓無形成の2例;流産に陥ると考えられる新たな異常例の報告), Photon Factory Activity Report 2013

2013年
軟骨最表層の構造

軟骨最表層の構造

7. Fujioka R, Aoyama T, Takakuwa T, The layered structure of the articular surface, Osteoarthritis Cartilage, 2013, 21, 1092-1098 doi: 10.1016/j.joca.2013.04.021(概要)[OpenAccess]

6. Shiraishi N, Nakashima T, Yamada S, Uwabe C, Kose K, Takakuwa T, Morphogenesis of lateral choroid plexus during human embryonic period, Anat Rec (Hoboken). 2013 Apr;296(4):692-700. doi: 10.1002/ar.22662(概要)[OpenAccess]

5. Hamabe Y, Hirose A, Yamada S, Uwabe C, Okada T, Togashi K, Kose K, Takakuwa T, Morphology and Morphometry of Fetal Liver at 16–26 Weeks of Gestation by Magnetic Resonance Imaging – Comparison with Embryonic Liver at Carnegie Stage 23, Hepatol Res,2013; 43: 639–647, doi: 10.1111/hepr.12000 (概要)

4. Shiraishi N, Yamada S, Takakuwa T. Three-dimensional Models Once Again – for research and teaching of early human development, Congenit Anom (Kyoto), 2013; 53(1), 58-59, doi: 10.1002/ar.22662 (概要)

査読なし

■ 高桑徹也、発生(第17章)、標準臨床検査学「基礎医学-人体の構造と機能」医学書院, P.332-340 (日本語総説)(外部紹介ページ)

2012年
外耳

外耳の動き(CS17-23)

3. Kagurasho M, Yamada S, Uwabe C, Kose K, Takakuwa T, Movement of the external ear in human embryo, Head Face Med. 2012 Feb 1;8(1):2, doi: 10.1186/1746-160X-8-2 (概要) 

2. Nakashima T, Hirose A, Yamada S, Uwabe C, Kose K, Takakuwa T, Morphometric analysis of the brain vesicles during the human embryonic period by magnetic resonance microscopic imaging, Congenit Anom (Kyoto). 2012 Mar;52(1):55-8, doi; 10.1111/j.1741-4520.2011.00345.x (概要), [OpenAccess]

1. Hirose A, Nakashima T, Yamada S, Uwabe C, Kose K, Takakuwa T, Embryonic liver morphology and morphometry by magnetic resonance microscopic imaging ,  Anat Rec (Hoboken). 2012 Jan;295(1):51-9., doi; 10.1002/ar.21496(概要) , [OpenAccess], (AR highlightsで紹介されました), [OpenAccess]

査読なし

■ Yamada S, Takakuwa T. (著書;editor)  the Human Embryo, InTech – Open Access Publisher, Rijeka, Croatia, 2012, 180P

–Yamada S, Takakuwa T, (執筆)Introduction: Overview of development in human embryos, P3-20.

–Yamada S, Nakashima T, Hirose A, Takakuwa T et al,(執筆)Developmental Anatomy of the Human Embryo: 3D-Imaging and Analytical Techniques, P111-126.

2011年脳室

■ Pyothorax-associated lymphoma: Loss of Epstein-Barr virus nuclear antigen-3B protein expression as a result of mismatch repair phenotypes, 健康科学(人間健康科学系専攻、紀要),2011;7:17-22

■ Tsuruyama T, Maruyama Y, Kanaya K, Takakuwa T et al, MLV integration induces the formation of transcription factor complexes on palindromic sequences in the Stat5a gene during the development of pre-B lymphomagenesis, Am J Pathol. 2011;178(3):1374-86, doi; 10.1016/j.ajpath.2010.12.012

査読なし

■ 塩田浩平、山田重人、土屋真衣子、中島 崇、高桑徹也、他;マイクロイメージング法を用いたヒト胚子・胎児の骨格系と中枢神経系の観察ならびにその定量的解析. 小児の脳神経 2011; 36(1): 1-6 (精神・神経疾患研究開発費ー総括研究報告書)

2010年

Tsuruyama T, Maruyama Y, Kanaya K, Takakuwa T et al. Dual retrovirus integration tagging: identification of new signaling molecules Fiz1 and Hipk2 that are involved in the IL-7 signaling pathway in B lylymphomas, J Leukoc Biol. 2010; 88(1):107-16.

Richard H. Kaszynski, Maruyama Y, Kanaya K, Takakuwa T et al, A quantitative trait locus responsible for inducing B‐cell lymphoblastic lymphoma is a hotspot for microsatellite instability, Cancer Sci, 2010; 101(3): 800-5

2009年

Oji Y, Takakuwa T, et al, WT1 IgG antibody for early detection of nonsmall cell lung cancer and as its prognostic factor. Int J Cancer. 2009;125(2):381-7. 2.

Takakuwa T, et al, Aberrant somatic hypermutations in thyroid lymphomas, Leukemia Research 2009 ;33(5):649-54.

2008年

Nur Rahadiani; Takakuwa T, et al, Latent membrane protein 1 of Epstein-Barr virus induces the expression of B-cell integration cluster, a precursor form of microRNA-155, in B lymphoma cell lines, BBRC, 2008;377(2):579-83.

Liu A, Takakuwa T, Fujita S, Luo WJ, Tresnasari K, van den Berg A, Poppema S, Aozasa K: ATRalterations in Hodgkin’s lymphoma. Oncology Report 19(4):999-1005, 2008.

Takakuwa T, Tresnasari K, Rahadiani N, Miwa H, Daibata M, Aozasa K, Cell origin of pyothorax-associated lymphoma; a lymphoma strongly associated with Epstein-Barr virus infection, Leukemia, 22(3):620-7, 2008.

Aozasa, K, Takakuwa T, Hongyo T, Yang W-I. Nasal NK/T-cell lymphoma: Epidemiology and pathogenesis. Int J Hematol ;87(2):110-7, 2008.

Inoue M, Takakuwa T, Minami M, Shiono H, Utsumi T, Kadota Y, Nasu T, Aozasa K, Okumura M, Clinicopathologic factors influencing postoperative prognosis in patients with small-sized adenocarcinoma of the lung, J Thorac Cardiovasc Surg;135(4):830-6, 2008

2007年

Tresnasari K, Takakuwa T, Ham MF, Rahadiani N, Nakajima H, Aozasa K.: Telomere dysfunction and inactivation of the p16(INK4a)/Rb pathway in pyothorax-associated lymphoma. Cancer Sci. 98(7):978-84, 2007.
Ham MF, Takakuwa T, Rahadiani N, Tresnasari K, Nakajima H, Aozasa K.: Condensin mutations and abnormal chromosomal structures in pyothorax-associated lymphoma. Cancer Sci.;98(7):1041-7, 2007.
Daibata M, Nemoto Y, Bandobashi K, Kotani N, Kuroda M, Tsuchiya M, Okuda H, Takakuwa T, Imai S, Shuin T, Taguchi H.: Promoter hypermethylation of the bone morphogenetic protein-6 gene in malignant lymphoma. Clin Cancer Res ;13:3528-35, 2007.

2006年

Hatano K, Ichimaru N, Takao T, Yoshimura K, Okuyama A, Takakuwa T, Aozasa K, Nakata Y, Okumoto Y, Hiraoka H. Paraganglioma of the urinary bladder: a case report. Hinyokika Kiyo. 52: 55-8, 2006.
Kurniawan AN, Hongyo T, Hardjolukito ESR, Ham MF, Takakuwa T, Kodariah R, Hoshida Y, Nomura T, Aozasa K: Gene mutation analysis of sinonasal lymphomas in Indonesia. Oncol Rep 15: 1257-63, 2006.
Takakuwa T, Ham MF, Luo WJ, Nakatsuka S, Daibata M, Aozasa K: Loss of expression of Epstein-Barr virus nuclear antigen-2 correlate with poor prognosis of pyothorax-associated lymphoma. Int J Cancer 52: 55-58, 2006.
Ishikawa SE, Nakatsuka S, Tomita Y, Fujita S, Nakamichi I, Takakuwa T, Sugiyama H, Fukuhara S, Hino M, Kanamaru A, Soma T, Tsukaguchi M, Igarashi K, Kanakura Y, Aozasa K, Osaka Lymphoma Study Group: Prognostic significance of BACH2 expression in diffuse large B- cell lymphoma. J Clin Oncol 23: 8012-7, 2006.
Ikeda JI, Morii E, Kimura H, Tomita Y, Takakuwa T, Hasegawa JI, Kim YK, Miyoshi Y, Noguchi S, Nishida T, Aozasa K: Epigenetic regulation of the expression of the novel stem cell marker CDCP1 in cancer cells. J Pathol 210: 75-84, 2006.
Liu A, Takakuwa T, Luo WJ, Fujita S, Aozasa K: Alterations in ATR in nasal NK/T-cell lymphoma and chronic active Epstein-Barr virus infection. Cancer Sci. 97:605-10, 2006
Ham MF, Takakuwa T, Luo WJ, Liu A, Horii A, Aozasa K: Impairment of double-strand breaks repair and aberrant splicing of ATM and MRE11 in leukemia-lymphoma cell lines with microsatellite instability. Cancer Sci. 97 :226-34, 2006.

2005年

Akimau P, Yoshia K, Hosotsubo H, Takakuwa T, Tanaka H, Sugimoto H: New experimental model of crush injury of hindlimbs in rats. J Trauma 58: 51-58, 2005.
Takakuwa T, Luo WJ, Ham MF, Wada N, Aozasa K: Identificatioan of Epstein-Barr virus integrated sites in lymphoblastoid cell line (IB4). Virus Research 108: 133-138, 2005.
Liu A, Takakuwa T, Fujita S, Ham MF, Luo WJ, Daibata M, Aozasa K: Alterations of DNA damage-response genes ATM and ATR in pyothorax-associated lymphoma. Lab Invest 85: 436-446, 2005.
Nakamichi I, Takakuwa T, Tanio Y, Iuchi K, Aozasa K. Pyothorax-associated lymphoma: an unusual case with both T- and B-cell genotypes. Virchows Arch: 447: 888-91, 2005
Aozasa K, Takakuwa T, Nakatsuka S: Pyothorax-associated lymphoma-a lymphoma developing in chronic inflammation. Adv Anat Pathol, 12: 324-31, 2005.

2004年

Nagasawa T, Takakuwa T, Takayama H, Dong Z, Miyagawa S, Itami S, Yoshikawa K, Aozasa K: Fas Gene Mutations in Mycosis fungoides: Analysis of Laser Capture-Microdissected Specimens from Cutaneous Lesions. Oncology 67: 130-134, 2004.
Nishiu M, Tomita Y, Nakatsuka S, Takakuwa T, Iizuka N, Hoshida Y, Ikeda J, Iuchi K, Yanagawa R, Nakamura Y, Aozasa K: Distinct pattern of gene expression in pyothorax-associated lymphoma (PAL), a lymphoma developing in long-standing inflammation. Cancer Sci 95: 828-834, 2004.
Takakuwa T, Luo WJ, Ham MF, Sakane-Ishikawa F, Wada N, Aozasa K: Integration of Epstein-Barr virus into chromosome 6q15 of Burkitt lymphoma cell line (Raji) induce loss of BACH2 expression. Am J Pathol 164: 967-974, 2004. (医学博士論文)
Luo WJ, Takakuwa T, Ham MF, Wada N, Liu A, Fujita S, Sakane-Ishikawa E, Aozasa K: Epstein-Barr virus is integrated between REL and BCL-11A in American Burkitt lymphoma cell line (NAB-2). Lab Invest 84: 1193-1199, 2004.
Miyazato H, Nakatsuka S, Dong Z, Takakuwa T, Oka K, Hanamoto H, Tatsumi Y, Kanamaru A, Aozasa K; Osaka Lymphoma Study Group: NK-cell related neoplasms in Osaka, Japan. Am J Hematol 76: 230-235, 2004.
Takakuwa T, Luo WJ, Ham MF, Aozasa K: A 50-bp Insertion from Intron 2 Between Exons 2 and 3 of NBS1 May be a Spliced Variant. Genes Chrom Cancer 39: 341-342, 2004.
Tsujimoto Y, Takakuwa T, Takayama H, Nishimura K, Okuyama A, Aozasa K, Nonomura N: In situ shortening of CAG repeat length within the androgen receptor gene in prostatic cancer and its possible precursors. Prostate 58: 283-290, 2004.

2003年

Takakuwa T, Luo WJ, Ham MF, Mizuki M, Iuchi K, Aozasa K: Establishment and characterization of unique cell lines derived from pyothorax-associated lymphoma which develops in long-standing pyothorax and strongly associated Epstein-Barr virus infection. Cancer Sci 94: 858-863, 2003.
Nakatsuka S, Liu A, Yao M, Takakuwa T, Tomita Y, Hoshida Y, Nishiu M, Aozasa K: Methylation of promoter region in p27 gene plays a role in the development of lymphoid malignancies. Int J Oncol 22: 561-568, 2003.
Nakatsuka S, Liu A, Dong Z, Nomura S, Takakuwa T, Miyazato H, Aozasa K; Osaka Lymphoma Study Group: Simian virus 40 sequences in malignant lymphomas in Japan. Cancer Res 63: 7606-7608, 2003.
Nakatsuka S, Takakuwa T, Tomita Y, Hoshida Y, Nishiu M, Yamaguchi M, Nishii K, Yang WI, Aozasa K: Hypermethylation of death-associated protein (DAP) kinase CpG island is frequent not only in B-cell but also in T- and natural killer (NK)/T-cell malignancies. Cancer Sci 94: 87-91, 2003.
青笹克之 星田義彦 高桑徹也: リンパ腫の発症機序2)ウイルス. 押味和夫(編) 悪性リンパ腫の基礎と臨床, 医薬ジャーナル社, pp45-52, 2003.

2002年

Takayama H, Takakuwa T, Tsujimoto Y, Tani Y, Nonomura N, Okuyama A, Nagata S, Aozasa K: Frequent mutations of FAS gene in testicular germ cell tumors. Am J Pathol 161: 635-641, 2002.
Takakuwa T, Dong Z, Nakatsuka S, Kojya S, Harabuchi Y, Yang WI, Nagata S, Aozasa K: Frequent mutations of Fas gene in nasal NK/T cell lymphoma. Oncogene 21: 4702-4705, 2002.
Dong Z, Takakuwa T, Takayama H, Luo WJ, Takano T, Amino N, Matsuzuka F, Aozasa K: Fas and Fas ligand gene mutations in Hashimoto’s Thyroiditis. Lab Invest 82: 1611-1616, 2002.
Hoshida Y, Hongyo T, Nakatsuka S, Nishiu M, Takakuwa T, Tomita Y, Nomura T, Aozasa K: Gene mutations in lymphoproliferative disorders of T and NK/T cell phenotypes developing in renal transplant patients. Lab Invest 82: 257-264, 2002.
Takayama H, Takakuwa T, Tsujimoto Y, Nonomura N, Okuyama A, Aozasa K: Analysisi of Fas gene mutations on laser capture microdissected specimens from renal cell carcinoma. Jpn J Cancer Res 93: 1201-1206, 2002
Miwa H, Takakuwa T, Nakatsuka S, Tomita Y, Iuchi K, Aozasa K: DNA sequence of immunoglobulin heavy chain variable region gene in pyothorax-associated lymphoma. Oncology 62: 241-250, 2002.
Yamauchi A, Tomita Y, Takakuwa T, Hoshida Y, Nakatsuka S, Sakamoto H, Aozasa K: PCR-based clonality analysis in thyroid lymphoma. Int J Molecular Medicine 10: 113-117, 2002
Nakatsuka S, Nishiu M, Tomita Y, Miwa H, Takakuwa T, Iuchi K, Yamamoto S, Aozasa K: Enhanced Expression of Neuron-specific Enolase (NSE) in Pyothorax-associated Lymphoma (PAL). Jpn J Cancer Res 93: 411-416, 2002.
鎌野寛、岡田泰士、山神真一、窪田良次、田中輝昭、高桑徹也: 運動の強度がヒトの免疫能に及ぼす効果について. 地域環境保健福祉研究 6: 1-6, 2002.
高桑徹也、遠藤重厚: スキーとスノーボードによる骨盤部外傷とその治療.整災外 45, 1255-1262, 2002

2001年

Nishimura R, Takakuwa T, Hoshida Y, Tsujimoto M, Aozasa K: Primary pancreatic lymphoma: clinicopathological analysis of 19 cases from Japan and review of the literature. Oncology 60: 322-329, 2001

Takakuwa T, Dong Z, Takayama H, Matsuzuka F, Nagata S, Aozasa K: Frequent mutations of Fas gene in thyroid lymphoma. Cancer Res 61: 1382-1385, 2001.
Takayama H, Takakuwa T, Dong Z, Nonomura N, Okuyama A, Nagata S, Aozasa K: Fas gene mutations in prostatic intraepithelial neoplasia and concurrent carcinoma: analysis of laser capture microdissected specimens. Lab Invest 81: 283-288, 2001.
Miwa H, Takakuwa T, Nakatsuka S, Tomita Y, Matsuzuka F, Aozasa K: DNA sequence of immunoglobulin heavy chain variable region gene in thyroid lymphoma. Jpn J Cancer Res 92: 1041-1047, 2001.
遠藤重厚、高桑徹也: スキー・スノーボード外傷とその治療と看護. Emerg Nursing 14: 26- 31, 2001
中塚伸一、高桑徹也、青笹克之: 悪性リンパ腫におけるDAP-kinase遺伝子のメチル化. 臨病理 49: 1242-1247, 2001.
青笹克之、高桑徹也、中塚伸一: 慢性炎症を基盤に発生する悪性リンパ腫. 日内科会誌 90: 75-79, 2001.
青笹克之、中塚伸一、高桑徹也: 慢性膿胸と悪性リンパ腫. Biotherapy 16: 153-160

2000年

Takakuwa T, Endo S, Shirakura Y, Yokoyama M, Tamatani M, Tohyama M, Aozasa K, Inada K: Interleukin-10 Gene Transfer Improves the Survival Rate of Mice Inoculated with E. coli. Critical Care Medicine 28: 2685-2689, 2000.
Takakuwa T, Nomura S, Matsuzuka F, Inoue H, Aozasa K: Expression of interleukin 7 and its receptor in thyroid lymphoma. Lab Invest 80: 1483-1490, 2000.
Takakuwa T, Hongyo T, Syaifudin M, Kanno H, Matsuzuka F, Narabayashi I, Nomura T, Aozasa K: Microsatellite instability and k-ras, p53 mutations in thyroid lymphoma. Jpn J Cancer Res 91: 280-286, 2000.
Nakatsuka S, Takakuwa T, Tomita Y, Miwa H, Matsuzuka F, Aozasa K: Role of hypermethylation of DAP-kinase CpG island in the development of thyroid lymphoma. Lab Invest 80: 1651-1655, 2000.